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ACD/ChemSketch screenshot
ACD/ChemSketch 2021.2.2   
... offers IUPAC chemical naming (up to 50 functional atoms); prediction of logP; comprehensive report creation; tautomer recognition; 2D structure cleaning; 3D optimization and viewing; drawing of polymers, organometallics, and Markush ...
Freeware

GNU Prolog for Windows  (x64 bit) screenshot
GNU Prolog for Windows (x64 bit) 1.5.0   
... facility under the interactive interpreter with completion on atoms. * powerful bidirectional interface between Prolog and C. # Compiler: * native-code compiler producing stand alone executables. * ...
Open Source
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